The role of somatostatin analogues in treatment of TSH secreting pituitary adenomas
نویسندگان
چکیده
Background TSH-secreting tumours are extremely rare case of hyperthyroidism. Most important clinical feature is preserved TSH level in subjects with apparent thyrotoxicosis. Possible misdiagnosis of primary thyroid hyperfunction could lead to mistreatment with anti-thyroid medications. This worsens disease course and outcome. Neurosurgery success rate is limited by tumour size and its extrasellar expansion. Native somatostatin is key negative regulator of TSH secretion. In most cases tumour cells express somatostatin receptors. This feature creates potential use of somatostatin analogues for medical treatment of TSHsecreting tumours.
منابع مشابه
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عنوان ژورنال:
دوره 6 شماره
صفحات -
تاریخ انتشار 2013